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CK 666

An Arp2/3 inhibitor

此產(chǎn)品僅用于科學(xué)研究，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)

庫存: 現(xiàn)貨

可選規(guī)格

包裝

價(jià)格

促銷價(jià)

數(shù)量
5mg

￥762.00

610.00

- +
10mg

￥1350.00

1080.00

- +
50mg

￥5450.00

4360.00

- +

已選 0 種 0 瓶

金額: ￥0.00

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貨號(hào): ajci12362
CAS: 442633-00-3
別名:
分子式: C18H17FN2O
分子量: 296.34
純度: ＞98%
溶解度: <29.63mg/ml in DMSO; <29.63mg/ml in ethanol
儲(chǔ)存: Store at -20°C
庫存: 現(xiàn)貨

Background

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1].

參考文獻(xiàn):
[1]. Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 2013 May 23;20(5):701-12.