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- GDP-α-D-mannose disodium(GDP-α-D-甘露糖)
GDP-α-D-mannose disodium(GDP-α-D-甘露糖)
GDP-α-D-mannose disodium 是甘露糖基轉(zhuǎn)移酶的供體底物，是 GDP-β-L-fucose 的前體。GDP-α-D-mannose disodium 對 GTP 具有競爭性抑制作用 (Ki 為 14.7 μM)，對 mannose-1-P 具有非競爭性抑制作用 (Ki 為 115 μM)。
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包裝價格促銷價數(shù)量
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5mg￥1125.001000.00- +
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10mg￥1750.001500.00- +
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50mg￥5000.004000.00- +
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100mg￥8500.007500.00- +
- 貨號: ajci76418
- CAS: 148296-46-2
- 別名: GDP-α-D-甘露糖；GDP-D-甘露糖二鈉;GDP-MANNOSE二鈉鹽;鳥苷5′-二磷酸-Α-D-甘露糖 二鈉鹽;鳥苷 5′-(三氫二磷酸酯) P′-ALPHA-D-甘露糖基酯二鈉鹽
- 分子式: C16H23N5Na2O16P2
- 分子量: 649.3
- 純度: ＞99%
- 溶解度: H2O : 100 mg/mL (154.01 mM; Need ultrasonic)
- 儲存: Store at -20°C
- 庫存: 現(xiàn)貨
Background
GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].
GDP-α-D-mannose is the alpha-anomer of GDP-D-mannose.
參考文獻：
[1]. Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7.
