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Formosanin C
Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.
Kaempferol
Kaempferol是一種黃酮類化合物,可作為ERRα和ERRγ的反向激動劑,具有抗氧化、抗炎和抗腫瘤活性。
ASTX660
A non-peptidomimetic inhibitor of IAP protein-peptide interactions
Arylquin 1
A Par-4 secretagogue
Ursonic acid
Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive deriv
Sinapinic acid (Sinapic acid)
A phenylpropanoid hydroxycinnamic acid with diverse biological activities
Taurodeoxycholic acid sodium hydrate
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. It activates S1PR2 pathway in addition to the TGR5 pathway.
ONC201
A TRAIL-inducing compound
ML-291
An activator of apoptosis through UPR
Schinifoline
Schinifoline,Zanthoxylum schinifolium Sieb中提取出來的一種喹啉酮衍生物,可促進(jìn)癌細(xì)胞放射敏感性,影響細(xì)胞循環(huán)周期和細(xì)胞凋亡。
PTC-028
A BMI1 inhibitor
SF1126
SF1126 是臨床相關(guān)的雙重 PI3K/BRD4 泛抑制劑,具有抗腫瘤和抗血管生成活性。SF1126 是 RGDS-綴合的 LY294002 前藥,其設(shè)計(jì)為表現(xiàn)出增加的溶解度并與腫瘤區(qū)室內(nèi)的特定整聯(lián)蛋白結(jié)合。SF1126 誘導(dǎo)細(xì)胞凋亡 (apoptosis)。
Terrestrosin D
Terrestrosin D 是從 Tribulus terrestris L. 中提取得到的一種甾體皂苷,可誘導(dǎo)細(xì)胞周期阻滯和癌細(xì)胞凋亡。Terrestrosin D 具有抗血管生成的活性。
Phytohemagglutinin
Phytohemagglutinin (PHA, Phaseolus vulgaris agglutinin) is expressed in Pichia pastoris using native signal peptides, or the Saccharomyces alpha-factor preprosequence, to direct proteins into the secretory pathway. Phytohemagglutinin induces apoptosis in
SS28
SS28是具有口服生物利用度的SRT501 類似物,可抑制微管蛋白聚合,在G2/M引起細(xì)胞周期阻滯。SS28會引起細(xì)胞凋亡而不是壞死。
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