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Durvalumab
Durvalumab (anti-PD-L1) is a selective, high affinity human IgG1 mAb that blocks programmed cell death ligand-1 (PD-L1) binding to PD-1 (IC50=0.1 nM) and CD80 (IC50=0.04 nM). MW=146.3 kDa.
Nivolumab (BMS-936558)
Nivolumab (BMS-936558) 是一種程序性死亡受體-1 (PD-1) 阻斷人 IgG4 抗體,用于治療晚期(轉(zhuǎn)移性)非小細(xì)胞肺癌。
PD-1-IN-1 (CA-170)
PD-1-IN-1 (CA-170) 是一種口服給藥的 VISTA 和 PD-L1 雙重抑制劑。
Atezolizumab (MPDL3280A)
Atezolizumab (MPDL3280A) (MPDL3280A) 是一種針對(duì)程序性死亡配體 1 (PD-L1) 的選擇性人源化單克隆 IgG1 抗體,用于癌癥研究。
BMS-8
An inhibitor of the PD-1/PD-L1 interaction
PD-166866
A potent inhibitor of FGFR1
PD-1-IN-17
An inhibitor of PD-1 signaling
PD-1/PD-L1 inhibitor 1 (BMS-1)
A PD-1/PD-L1 interaction inhibitor
NP-12
A PL-1/PD-L interaction inhibitor
PD-159020
PD-159020是一種非選擇性的ETA/ETB拮抗劑,對(duì)hETA和hETB的IC50值分別為30和50nM。
PD-1-IN-22
PD-1-IN-22 是一種有效的程序性細(xì)胞死亡 1 (PD-1)/程序性細(xì)胞死亡配體1 (PD-L1) 相互作用的抑制劑,IC50 為 92.3 nM。
Avelumab (Anti-Human PD-L1, Human Antibody)
Avelumab (anti-PD-L1) (Bavencio, MSB0010718C) is a fully human IgG1 monoclonal antibody that targets the protein programmed death-ligand 1 (PD-L1). Avelumab exhibits potential antibody-dependent cell-mediated cytotoxicity and is used for the treatment of
CMPD-1
A substrate-selective p38α MAPK inhibitor
PD-1/PD-L1 Inhibitor 3
PD-1/PD-L1 inhibitor 2
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